GW 501516 (Cardarine) – 50MG per vial

Clinical Test Expectation – GW 501516 (Cardarine) – Human Subjects : Increase endurance. Weight loss. Benefits for diabetics. Improved blood fat levels
Strength – 50MG per vial

Introduction
Athletes and dedicated gym-goers are sometimes willing to use a number of substances to push the boundaries of sports performance and physique enhancement. While some compounds can be quite effective for boosting performance, their safety is often highly questionable. One such substance is Cardarine, a controversial drug touted to promote weight loss and improve sports performance. However, data on its effectiveness and safety is extremely limited.

Cardarine, also referred to as GW501516, is a synthetic compound that serves as a metabolic modulator. People often think it’s a type of compound called a SARM (selective androgen receptor modulator), but Cardarine actually belongs to a class of drugs called peroxisome proliferator-activated receptor (PPAR) agonists.

The cell receptors these affect are most abundant in muscle cells throughout the body. Compounds such as Cardarine act upon energy metabolism in the cells and are thought to increase energy expenditure.

This is why some athletes and bodybuilders are attracted to taking Cardarine. They may take it in hopes of increasing fat-burning, getting a leaner body composition, and increasing their sport performance.

Weight Loss
Two major purported benefits of taking Cardarine are weight loss and fat loss. In theory, it may be able to increase fat burning capacity. This may be because the drug serves as a metabolic modulator by targeting a part of the cell that handles energy metabolism. Initial studies on Cardarine looked at its potential as a treatment for obesity.

An older study in mice found that Cardarine increased fatty acid oxidation resulting in less fat storage, reducing the incidence of obesity in mice given a high-calorie diet. Researchers later suggested that Cardarine may stimulate PPAR in a similar way to exercise, so that taking it might mimic the effect of exercise in the body.

If that were the case, it would mean people could use Cardarine to get some of the benefits of exercising without actually needing to exercise. Unfortunately,

Benefits for those with Diabetes
Researchers also investigated GW 501516 (Cardarine) for the prevention of type 2 diabetes, a condition in which the body becomes resistant to insulin and thereby unable to efficiently process carbohydrates. A more recent rodent study looked at the effect of using Cardarine on gestational diabetes, a condition in which pregnant people experience high blood sugar.

They found that rats with gestational diabetes treated with Cardarine had improvements in blood glucose and insulin levels, and less damage to their islet cells, the cells in the pancreas that produce insulin. Lastly, one study actually found that Cardarine may help accelerate the healing of diabetic wounds, which people with advanced diabetes often develop due to a reduction in blood flow to certain body parts.

As you can see, most of the research in this area is in animals. Thus, even though the outcomes showed potential, they cannot be applied to humans legally, and more research is needed.

May improve blood fat levels
Among the initial theorized uses for Cardarine was to improve blood lipid levels, which include your levels of the fats known as cholesterol and triglycerides.

It’s well documented in older research that a link exists between the PPAR pathway and fat burning. That said, only a limited number of studies have suggested that drugs such as Cardarine may affect fats in the blood. One such human study from 2007 took a small group of 24 healthy volunteers and gave them either a placebo, 2.5 mg of Cardarine, or 10 mg of Cardarine per day over a 2-week period.

They found that the groups that received Cardarine experienced an increase in HDL (good) cholesterol, and a reduction in blood triglycerides. While these results are promising, this study design has not been replicated on a larger, long-term scale, thus recommendations cannot be made.

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